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Bryan D Choi Selected Research

Immunotherapy

4/2024Immunotherapy for Brain Tumors: Where We Have Been, and Where Do We Go From Here?
2/2024Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
1/2023Labeling T Cells to Track Immune Response to Immunotherapy in Glioblastoma.
1/2022Implications of IDH mutations on immunotherapeutic strategies for malignant glioma.
11/2021Human prostate cancer bone metastases have an actionable immunosuppressive microenvironment.
10/2020Immune Therapy for Central Nervous System Metastasis.
10/2020Checkpoint inhibitor immunotherapy for glioblastoma: current progress, challenges and future outlook.
1/2019A novel in situ multiplex immunofluorescence panel for the assessment of tumor immunopathology and response to virotherapy in pediatric glioblastoma reveals a role for checkpoint protein inhibition.
1/2019Immunotherapy for Glioblastoma: Adoptive T-cell Strategies.
1/2018Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma.
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Bryan D Choi Research Topics

Disease

44Neoplasms (Cancer)
05/2024 - 10/2009
28Glioblastoma (Glioblastoma Multiforme)
04/2024 - 01/2013
17Glioma (Gliomas)
02/2024 - 10/2009
9Brain Neoplasms (Brain Tumor)
04/2024 - 01/2011
7Bites and Stings (Sting)
01/2019 - 07/2011
5Lymphopenia (Lymphocytopenia)
01/2018 - 01/2013
3Lymphoma (Lymphomas)
05/2024 - 12/2019
3Hematologic Neoplasms (Hematological Malignancy)
01/2023 - 01/2018
3Neoplasm Metastasis (Metastasis)
11/2021 - 10/2020
3Melanoma (Melanoma, Malignant)
10/2020 - 01/2013
2Astrocytoma (Pilocytic Astrocytoma)
02/2024 - 01/2024
2Renal Cell Carcinoma (Grawitz Tumor)
11/2020 - 10/2020
2Lung Neoplasms (Lung Cancer)
10/2020 - 11/2018
1Meningioma (Meningiomas)
02/2024
1Adenocarcinoma
02/2024
1Pancreatic Neoplasms (Pancreatic Cancer)
02/2024
1Disease Progression
08/2023
1Prostatic Neoplasms (Prostate Cancer)
11/2021
1Non-Hodgkin Lymphoma (Lymphosarcoma)
12/2019
1B-Cell Lymphoma (Lymphoma, B Cell)
12/2019
1Multiple Myeloma
11/2019
1Seizures (Absence Seizure)
03/2019
1Autoimmune Diseases (Autoimmune Disease)
01/2019
1Graft vs Host Disease (Graft-Versus-Host Disease)
01/2019
1Herpes Simplex
01/2019
1Experimental Melanoma
01/2019
1Meningomyelocele (Myelomeningocele)
01/2018
1Virus Diseases (Viral Diseases)
08/2015
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
06/2015
1Extranodal Extension
01/2014
1Carcinogenesis
12/2012

Drug/Important Bio-Agent (IBA)

21Chimeric Antigen ReceptorsIBA
05/2024 - 01/2014
18epidermal growth factor receptor VIIIIBA
01/2023 - 10/2009
12ErbB Receptors (EGF Receptor)IBA
03/2024 - 10/2009
11AntigensIBA
03/2024 - 01/2013
8Temozolomide (Temodar)FDA LinkGeneric
11/2023 - 01/2013
6VaccinesIBA
01/2022 - 12/2012
4Proteins (Proteins, Gene)FDA Link
03/2024 - 01/2019
4Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
01/2024 - 06/2013
3RNA (Ribonucleic Acid)IBA
02/2024 - 08/2023
3Neoplasm Antigens (Tumor Antigens)IBA
01/2019 - 02/2014
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
08/2017 - 10/2009
3Bispecific AntibodiesIBA
06/2015 - 07/2011
3EnzymesIBA
06/2013 - 11/2012
3Peptides (Polypeptides)IBA
03/2013 - 10/2009
2Biomarkers (Surrogate Marker)IBA
01/2022 - 11/2018
2Immune Checkpoint InhibitorsIBA
01/2022 - 10/2020
2Phosphotransferases (Kinase)IBA
11/2020 - 03/2019
2Single-Chain AntibodiesIBA
12/2019 - 01/2018
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
03/2019 - 03/2013
2Granzymes (Granzyme)IBA
12/2013 - 09/2013
1EpitopesIBA
02/2024
1Small Cytoplasmic RNAIBA
02/2024
1AcidsIBA
02/2024
1CesiumIBA
02/2024
1MesothelinIBA
02/2024
1Monoclonal AntibodiesIBA
11/2023
1AntibodiesIBA
11/2023
1bavituximabIBA
08/2023
1Azacitidine (5 Azacytidine)FDA Link
01/2022
1alpha-hydroxyglutarateIBA
01/2022
1Therapeutic UsesIBA
11/2021
1TOR Serine-Threonine KinasesIBA
11/2020
1Tyrosine (L-Tyrosine)FDA Link
11/2020
1tisagenlecleucelIBA
12/2019
1CD19 AntigensIBA
12/2019
1LigandsIBA
11/2019
1tyrosine receptor (receptor, tyrosine)IBA
03/2019
1Anticonvulsants (Antiepileptic Drugs)IBA
03/2019
1Genetic Markers (Genetic Marker)IBA
03/2019
1Interleukin-2 (IL2)IBA
01/2019
1Immunologic Factors (Immunomodulators)IBA
06/2017
1Interleukin-10 (Interleukin 10)IBA
02/2016
1B-Cell Activating FactorIBA
02/2016
1blinatumomabIBA
06/2015
1PerforinIBA
12/2013
1Complementarity Determining Regions (Complementarity Determining Region)IBA
09/2013
1Antineoplastic Agents (Antineoplastics)IBA
04/2013
1rindopepimutIBA
03/2013
1Alkylating AgentsIBA
01/2013
1Protein Subunit VaccinesIBA
01/2013
1Cancer VaccinesIBA
12/2012
1Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA
11/2012
1adipic acid (adipate)IBA
11/2012
1isocitric acid (isocitrate)IBA
11/2012
1homoisocitric acidIBA
11/2012
1Oxidoreductases (Dehydrogenase)IBA
11/2012
1Immunotoxins (Immunotoxin)IBA
01/2011

Therapy/Procedure

26Immunotherapy
04/2024 - 10/2009
21Therapeutics
01/2024 - 10/2009
7Drug Therapy (Chemotherapy)
11/2023 - 01/2013
4Radiotherapy
02/2024 - 07/2013
3Craniotomy
02/2024 - 01/2012
1Intraventricular Infusions
03/2024
1Brachytherapy
02/2024
1Cell- and Tissue-Based Therapy (Cell Therapy)
01/2020
1Intravenous Administration
11/2019
1Organ Transplantation
01/2019
1Oncolytic Virotherapy
01/2019
1Conservative Treatment
01/2018